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Physiology

What is the endocannabinoid system?

Discovered by scientists in the early 1990s, the endocannabinoid system is responsible for regulating many...
Physiology

The ECS as a Framework for Understanding Health and Healing

Why the ECS may help bridge physiology, lived experience, and individualized care Over the previous...
By Dr. Uwe Blesching, Ph.D.
Physiology

Why So Many Clinicians Are Curious – Yet Still Hesitant

Part 3 of the series: Navigating cannabinoid medicine in a rapidly changing clinical landscape In...
By Dr. Uwe Blesching, Ph.D.
Physiology

Why So Many Patients Feel Lost in Cannabinoid Medicine: Living Between Chronic Symptoms, Conflicting Information, and the Search for Better Answers

In Part 1 of this series, I explored how healthcare is changing and why many...
By Dr. Uwe Blesching, Ph.D.
Physiology

From AIDS Wards to Dispensaries: The LGBTQ Activists Who Built Medical Cannabis

With Pride Month approaching and the DEA’s first formal rescheduling order on the books, the...
By The Cannigma Team
Physiology

A Changing Landscape in Health and Healing – Why More Patients, Clinicians, and Cannabis Professionals Are Searching for Better Frameworks

Something important is happening in health and medicine, and most people can feel it even...
By Dr. Uwe Blesching, Ph.D.
Physiology

Too High on Cannabis? What’s Actually Happening in Your Brain, and What the Evidence Says About Coming Down

A pharmacology-grounded look at what THC does to the brain’s fear circuitry when you get...
By The Cannigma Team
Physiology

Cannabis Side Effects Explained: The Science Behind Dry Mouth, Red Eyes, Couch Lock, and the Giggles

A pharmacology-grounded look at what’s happening in your body during cannabis’s most recognizable moments, from...
By The Cannigma Team
Physiology

How Cannabis Consumption Methods Shape Your High: The Science Behind Each Delivery Method

From edibles to dabbing to nanoemulsion beverages, cannabis delivery methods produce distinct biological effects. The...
By The Cannigma Team
Physiology

Seasonal Endocannabinoid System Changes: How Light, Mood, and Sleep Shift With the Year

Your body doesn’t ignore the calendar. Immune function, hormone levels, gut bacteria, even body weight...
By The Cannigma Team
Physiology

The Endocannabinoid System and Nutrition: How to Restore Regulatory Balance This Spring

Every year when spring comes around, people talk about resetting. Detoxing. Cleaning things up. Starting...
By Sherri and Elisabeth Mack
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